Projects 14140-14151

Cause: influenza

These projects simulate the folding of several designed mini-proteins that target influenza haemagglutinin and botulinum neurotoxin B. We are trying to understand the folding landscape of these designs in solvent and estimate how mutations change the folding landscape. This is a collaboration with David Baker lab at University of Washington.

List of Contributors

This project is managed by Prof. Vincent Voelz at Temple University.

Dr. Voelz's research focuses on using new simulation methods to unravel the mysteries of how proteins self-assemble into their functional folds, and to design folding and binding properties of proteins and peptide mimetics from first principles. The Voelz Lab participates in the Folding@home project, hosting two servers at Temple University. Dr. Voelz was formerly a postdoctoral scholar in the Vijay Pande lab at Stanford University.

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